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Progress of three-dimensional macroporous bioactive glass for bone regeneration

Lijun JI, Yunfeng SI, Ailing LI, Wenjun WANG, Dong QIU, Aiping ZHU

《化学科学与工程前沿（英文）》 2012年 第6卷 第4期   页码 470-483 doi: 10.1007/s11705-012-1217-1

摘要： Bioactive glasses (BGs) are ideal materials for macroporous scaffolds due to their excellent osteoconductive, osteoinductive, biocompatible and biodegradable properties, and their high bone bonding rates. Macroporous scaffolds made from BGs are in high demand for bone regeneration because they can stimulate vascularized bone ingrowth and they enhance bonding between scaffolds and surrounding tissues. Engineering BG/biopolymers (BP) composites or hybrids may be a good way to prepare macroporous scaffolds with excellent properties. This paper summarizes the progress in the past few years in preparing three-dimensional macroporous BG and BG/BP scaffolds for bone regeneration. Since the brittleness of BGs is a major problem in developing macroporous scaffolds and this limits their use in load bearing applications, the mechanical properties of macroporous scaffolds are particularly emphasized in this review.

关键词： bioactive glass     biopolymer     bone regeneration     macroporous scaffolds     tissue engineering    

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Development and clinical trial of a novel bioactive bone cement

LEONG John, LI Zhaoyang, LU William

《医学前沿（英文）》 2008年 第2卷 第2期   页码 117-126 doi: 10.1007/s11684-008-0022-1

摘要： Strontium (Sr) and related compounds have become more attractive in the prevention and treatment of osteoporosis. Previously, we developed a novel bioactive bone cement which is mainly composed of strontium-containing hydroxyapatite (Sr-HA) filler and bisphenol A diglycidylether dimethacrylate (Bis-GMA) resin. This bone cement is superior to conventional polymethylmethacrylate (PMMA) bone cement in bioactivity, biocompatibility, and osseointegration. It also has shown sufficient mechanical strength properties for its use in percutaneous vertebroplasty (PVP) and total hip replacement (THR). In this paper, we review the and clinical evidence for the effectiveness of this bioactive bone cement.

关键词： bioactivity     effectiveness     strontium-containing hydroxyapatite     osseointegration     sufficient mechanical    

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Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive molecules

Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li

《化学科学与工程前沿（英文）》 2022年 第16卷 第1期   页码 4-33 doi: 10.1007/s11705-021-2041-2

摘要： The interrelationships and synergistic regulations of bioactive molecules play pivotal roles in physiological and pathological processes involved in the initiation and development of some diseases, such as cancer and neurodegenerative and cardiovascular diseases. Therefore, the simultaneous, accurate and timely detection of two bioactive molecules is crucial to explore their roles and pathological mechanisms in related diseases. Fluorescence imaging associated with small molecular probes has been widely used in the imaging of bioactive molecules in living cells and due to its excellent performances, including high sensitivity and selectivity, noninvasive properties, real-time and high spatial temporal resolution. Single organic molecule fluorescent probes have been successively developed to simultaneously monitor two biomolecules to uncover their synergistic relationships in living systems. Hence, in this review, we focus on summarizing the design strategies, classifications, and bioimaging applications of dual-response fluorescent probes over the past decade. Furthermore, future research directions in this field are proposed.

关键词： bioactive molecules     fluorescent probes     in living cells and in vivo     review    

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An investigation into the properties of ternary and binary cement pastes containing glass powder

Marcelo Frota BAZHUNI, Mahsa KAMALI, Ali GHAHREMANINEZHAD

《结构与土木工程前沿（英文）》 2019年 第13卷 第3期   页码 741-750 doi: 10.1007/s11709-018-0511-5

摘要： The properties of binary and ternary cement pastes containing glass powder (GP) were examined. Hydration at early age was evaluated using semi-adiabatic calorimetry and at late ages using non-evaporable water content and thermogravimetric analysis. The transport characteristic was assessed by measuring electrical resistivity. The binary paste with slag showed the highest hydration activity compared to the binary pastes with GP and fly ash (FA). The results indicated that the pozzolanic behavior of the binary paste with GP was less than that of the binary pastes with slag or FA at late ages. An increase in the electrical resistivity and compressive strength of the binary paste with GP compared to other modified pastes at late ages was observed. It was shown that GP tends to increase the drying shrinkage of the pastes. Ternary pastes containing GP did not exhibit synergistic enhancements compared to the respective binary pastes.

关键词： cement paste     glass powder     pozzolanic reaction     supplementary cementitious material    

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Precision glass molding: Toward an optimal fabrication of optical lenses

Liangchi ZHANG,Weidong LIU

《机械工程前沿（英文）》 2017年 第12卷 第1期   页码 3-17 doi: 10.1007/s11465-017-0408-3

摘要：

It is costly and time consuming to use machining processes, such as grinding, polishing and lapping, to produce optical glass lenses with complex features. Precision glass molding (PGM) has thus been developed to realize an efficient manufacture of such optical components in a single step. However, PGM faces various technical challenges. For example, a PGM process must be carried out within the super-cooled region of optical glass above its glass transition temperature, in which the material has an unstable non-equilibrium structure. Within a narrow window of allowable temperature variation, the glass viscosity can change from 105 to 1012 Pa·s due to the kinetic fragility of the super-cooled liquid. This makes a PGM process sensitive to its molding temperature. In addition, because of the structural relaxation in this temperature window, the atomic structure that governs the material properties is strongly dependent on time and thermal history. Such complexity often leads to residual stresses and shape distortion in a lens molded, causing unexpected changes in density and refractive index. This review will discuss some of the central issues in PGM processes and provide a method based on a manufacturing chain consideration from mold material selection, property and deformation characterization of optical glass to process optimization. The realization of such optimization is a necessary step for the Industry 4.0 of PGM.

关键词： precision glass molding     optical lens     constitutive modeling     optimization     manufacturing chain     Industry 4.0    

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Nonlinear analysis of pre-tensioned glass wall facade by stability function with initial imperfection

Siu-Lai CHAN, Yaopeng LIU, Andy LEE,

《结构与土木工程前沿（英文）》 2010年 第4卷 第3期   页码 376-382 doi: 10.1007/s11709-010-0086-2

摘要： Pre-tensioned high strength trusses using alloy steel bar are widely used as glass wall supporting systems because of the high degree of transparency. The breakage of glass panes in this type of system occurs occasionally, likely to be due to error in design and analysis in addition to other factors like glass impurity and stress concentration around opening in a spider system. Most design does not consider the flexibility of supports from finite stiffness of supporting steel or reinforced concrete beams. The resistance of lateral wind pressure of the system makes use of high tension force coupled with the large deflection effect, both of which are affected by many parameters not generally considered in conventional structures. In the design, one must therefore give a careful consideration on various effects, such as support settlement due to live loads and material creep, temperature change, pre-tension force, and wind pressure. It is not uncommon to see many similar glass wall systems fail in the wind load test chambers under a design wind speed. This paper presents a rigorous analysis and design of this type of structural systems used in a project in Hong Kong, China. The stability function with initial curvature is used in place of the cubic function, which is only accurate for linear analysis. The considerations and analysis techniques are believed to be of value to engineers involved in the design of the structural systems behaving nonlinearly.

关键词： tension system     glass wall     nonlinear analysis     pre-tensioning     second-order analysis    

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Bioactive hyaluronic acid fragments inhibit lipopolysaccharide-induced inflammatory responses via the

Na You, Sasa Chu, Binggang Cai, Youfang Gao, Mizhou Hui, Jin Zhu, Maorong Wang

《医学前沿（英文）》 2021年 第15卷 第2期   页码 292-301 doi: 10.1007/s11684-020-0806-5

摘要： The high- and the low-molecular weight hyaluronic acids (HMW-HA and LMW-HA, respectively) showed different biological activities in inflammation. However, the role of LMW-HA in inflammatory response is controversial. In this study, we aimed to investigate the effect of bioactive hyaluronan (B-HA) on lipopolysaccharide (LPS)-induced inflammatory responses in human macrophages and mice. B-HA was produced from HA treated with glycosylated recombinant human hyaluronidase PH20. Human THP-1 cells were induced to differentiate into macrophages. THP-1-derived macrophages were treated with B-HA, LPS, or B-HA+LPS. The mRNA expression and the production of inflammatory cytokines were determined using quantitative real-time PCR and enzyme-linked immunosorbent assay. The phosphorylation levels of proteins in the nuclear factor- B (NF- B), mitogen-activated protein kinase (MAPK), and IRF-3 signaling pathways were measured using Western blot. The efficacy of B-HA was assessed in a mouse model of LPS-induced inflammation. Results showed that B-HA inhibited the expression of TNF-α, IL-6, IL-1, and IFN-β, and enhanced the expression of the anti-inflammatory cytokine IL-10 in LPS-induced inflammatory responses in THP-1-derived macrophages and . B-HA significantly suppressed the phosphorylation of the TLR4 signaling pathway proteins p65, IKKα/β, I Bα, JNK1/2, ERK1/2, p38, and IRF-3. In conclusion, our results demonstrated that the B-HA attenuated the LPS-stimulated inflammatory response by inhibiting the activation of the TLR4 signaling pathway. B-HA could be a potential anti-inflammatory drug in the treatment of inflammatory disease.

关键词： bioactive hyaluronan     lipopolysaccharide     inflammatory cytokines     TLR4     human macrophages    

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Influence of damages on static behavior of single-layer cable net supported glass curtain wall: full-scale

Gang SHI, Yongjiu SHI, Yuanqing WANG, Yongzhi ZUO, Xiaohao SHI, Zaoyang GUO,

《结构与土木工程前沿（英文）》 2010年 第4卷 第3期   页码 383-395 doi: 10.1007/s11709-010-0074-6

摘要： The single-layer cable net supported glass curtain wall has been applied in many building structures all over the world. In service, it will inevitably be subject to various damages. To study the influence of such damages on the static behavior of the single-layer cable net supported glass curtain wall, a full-scale model with the outside outline size of 4.85 m × 4.85 m and 4 × 4 grids is designed and tested. Two kinds of damages that are the cable prestress loss and cable anchorage end failure are led into the structure model during the test, and their influence has been investigated. The stiffness contribution of glass panels to the single-layer cable net supported glass curtain wall structure with or without damages and its change have been tested and analyzed. The results show that the maximum change rate of nodal deflection is 13.78% for the damage of cable prestress loss, while the change rate of nodal deflection is between 7% and 22% for the damage of cable anchorage end failure. The influence degree of the damages depends on the ratio of the structure initial stress stiffness change caused by damages to the total stiffness of the structure. The stiffness contribution of glass panels increases with the load increase. Under the same loading condition, the stiffness contribution of glass panels to the damaged structure is greater than that to the intact structure. The stiffness contribution of glass panels reduces the effect of the damages on the structural displacement and the cable tension force, but the glass panel could break if its stiffness contribution is too large.

关键词： single-layer plane cable net supported glass curtain wall     damage     cable prestress loss     cable anchorage end failure     stiffness contribution of glass panels    

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Recycled glass replacement as fine aggregate in self-compacting concrete

Yasser SHARIFI, Mahmoud HOUSHIAR, Behnam AGHEBATI

《结构与土木工程前沿（英文）》 2013年 第7卷 第4期   页码 419-428 doi: 10.1007/s11709-013-0224-8

摘要： With increasing environmental pressure to reduce solid waste and to recycle as much as possible, the concrete industry has adopted a number of methods to achieve this goal by replacement of waste glass with concrete composition materials. Due to differences in mixture design, placement and consolidation techniques, the strength and durability of Self Compacting Concrete (SCC) may be different than those of conventional concrete. Therefore, replacement of waste glass with fine aggregate in SCC should deeply be investigated compared to conventional concretes. The aim of the present study is to investigate the effect of glass replacement with fine aggregate on the SCC properties. In present study, fine aggregate has been replaced with waste glass in six different weight ratios ranging from 0% to 50%. Fresh results indicate that the flow-ability characteristics have been increased as the waste glass incorporated to paste volume. Nevertheless, compressive, flexural and splitting strengths of concrete containing waste glass have been shown to decrease when the content of waste glass is increased. The strength reduction of concrete in different glass replacement ratios is not remarkable, thus it can be produced SCC with waste glass as fine aggregate in a standard manner.

关键词： Self Compacting Concrete (SCC)     recycle glass     fine aggregate     fresh and hardened properties    

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Review of small aspheric glass lens molding technologies

Shaohui YIN,Hongpeng JIA,Guanhua ZHANG,Fengjun CHEN,Kejun ZHU

《机械工程前沿（英文）》 2017年 第12卷 第1期   页码 66-76 doi: 10.1007/s11465-017-0417-2

摘要：

Aspheric lens can eliminate spherical aberrations, coma, astigmatism, field distortions, and other adverse factors. This type of lens can also reduce the loss of light energy and obtain high-quality images and optical characteristics. The demand for aspheric lens has increased in recent years because of its advantageous use in the electronics industry, particularly for compact, portable devices and high-performance products. As an advanced manufacturing technology, the glass lens molding process has been recognized as a low-cost and high-efficiency manufacturing technology for machining small-diameter aspheric lens for industrial production. However, the residual stress and profile deviation of the glass lens are greatly affected by various key technologies for glass lens molding, including glass and mold-die material forming, mold-die machining, and lens molding. These key technical factors, which affect the quality of the glass lens molding process, are systematically discussed and reviewed to solve the existing technical bottlenecks and problems, as well as to predict the potential applicability of glass lens molding in the future.

关键词： aspheric glass lens     mold-die manufacturing     lens molding     molding process simulation    

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Recent advancements in optical microstructure fabrication through glass molding process

Tianfeng ZHOU,Xiaohua LIU,Zhiqiang LIANG,Yang LIU,Jiaqing XIE,Xibin WANG

《机械工程前沿（英文）》 2017年 第12卷 第1期   页码 46-65 doi: 10.1007/s11465-017-0425-2

摘要：

Optical microstructures are increasingly applied in several fields, such as optical systems, precision measurement, and microfluid chips. Microstructures include microgrooves, microprisms, and microlenses. This paper presents an overview of optical microstructure fabrication through glass molding and highlights the applications of optical microstructures in mold fabrication and glass molding. The glass-mold interface friction and adhesion are also discussed. Moreover, the latest advancements in glass molding technologies are detailed, including new mold materials and their fabrication methods, viscoelastic constitutive modeling of glass, and microstructure molding process, as well as ultrasonic vibration-assisted molding technology.

关键词： optical microstructure     microgroove     microlens     glass molding process     single-point diamond cutting    

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Assessment of glass fiber-reinforced polyester pipe powder in soil improvement

《结构与土木工程前沿（英文）》 2021年 第15卷 第3期   页码 742-753 doi: 10.1007/s11709-021-0732-x

摘要： This study investigates the use of glass fiber-reinforced polyester (GRP) pipe powder (PP) for improving the bearing capacity of sandy soils. After a series of direct share tests, the optimum PP addition for improving the bearing capacity of soils was found to be 12%. Then, using the optimum PP addition, the bearing capacity of the soil was estimated through a series of loading tests on a shallow foundation model placed in a test box. The bearing capacity of sandy soil was improved by up to 30.7%. The ratio of the depth of the PP-reinforced soil to the diameter of the foundation model (H/D) of 1.25 could sufficiently strengthen sandy soil when the optimum PP ratio was used. Microstructural analyses showed that the increase in the bearing capacity can be attributed to the chopped fibers in the PP and their multiaxial distribution in the soil. Besides improving the engineering properties of soils, using PP as an additive in soils would reduce the accumulation of the industrial waste, thus providing a twofold benefit.

关键词： shallow foundation     sandy soil     bearing capacity     soil improvement     pipe powder    

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Mechanical properties of steel, glass, and hybrid fiber reinforced reactive powder concrete

Atheer H.M. ALGBURI, M. Neaz SHEIKH, Muhammad N.S. HADI

《结构与土木工程前沿（英文）》 2019年 第13卷 第4期   页码 998-1006 doi: 10.1007/s11709-019-0533-7

摘要： This study examines the properties of fiber-reinforced reactive powder concrete (FR-RPC). Steel fibers, glass fibers, and steel-glass hybrid fibers were used to prepare the FR-RPC. The non-fibrous reactive powder concrete (NF-RPC) was prepared as a reference mix. The proportion of fibers by volume for all FR-RPC mixes was 1.5%. Steel fibers of 13 mm length and 0.2 mm diameter were used to prepare the steel fiber-reinforced RPC (SFR-RPC). Glass fibers of 13 mm length and 1.3 mm diameter were used to prepare the glass fiber-reinforced RPC (GFR-RPC). The hybrid fiber-reinforced RPC (HFR-RPC) was prepared by mixing 0.9% steel fibers and 0.6% glass fibers. Compressive strength, axial load-axial deformation behavior, modulus of elasticity, indirect tensile strength, and shear strength of the RPC mixes were investigated. The results showed that SFR-RPC achieved higher compressive strength, indirect tensile strength and shear strength than NF-RPC, GFR-RPC, and HFR-RPC. Although the compressive strengths of GFR-RPC and HFR-RPC were slightly lower than the compressive strength of NF-RPC, the shear strengths of GFR-RPC and HFR-RPC were higher than that of NF-RPC.

关键词： reactive powder concrete     steel fiber     glass fiber     hybrid fiber    

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Fatigue shear performance of concrete beams reinforced with hybrid (glass-fiber-reinforced polymer+ steel

《结构与土木工程前沿（英文）》 2021年 第15卷 第3期   页码 576-594 doi: 10.1007/s11709-021-0728-6

摘要： Reinforced concrete beams consisting of both steel and glass-fiber-reinforced polymer rebars exhibit excellent strength, serviceability, and durability. However, the fatigue shear performance of such beams is unclear. Therefore, beams with hybrid longitudinal bars and hybrid stirrups were designed, and fatigue shear tests were performed. For specimens that failed by fatigue shear, all the glass-fiber-reinforced polymer stirrups and some steel stirrups fractured at the critical diagonal crack. For the specimen that failed by the static test after 8 million fatigue cycles, the static capacity after fatigue did not significantly decrease compared with the calculated value. The initial fatigue level has a greater influence on the crack development and fatigue life than the fatigue level in the later phase. The fatigue strength of the glass-fiber-reinforced polymer stirrups in the specimens was considerably lower than that of the axial tension tests on the glass-fiber-reinforced polymer bar in air and beam-hinge tests on the glass-fiber-reinforced polymer bar, and the failure modes were different. Glass-fiber-reinforced polymer stirrups were subjected to fatigue tension and shear, and failed owing to shear.

关键词： fatigue     shear     hybrid stirrups     hybrid reinforcement     fiber-reinforced polymer    

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Realization of energy-saving glass using photonic crystals

Yen-Hsiang CHEN, Li-Hung LIAO, Yu-Bin CHEN

《能源前沿（英文）》 2018年 第12卷 第1期   页码 178-184 doi: 10.1007/s11708-018-0523-9

摘要： This work successfully developed an energy-saving glass with wavelength selectivity. The glass is composed of a SiO substrate and two layers of three-dimensional photonic crystals. Each crystal is composed of identical and transparent polystyrene spheres after their self-assembling. The glass then possesses dual photonic band gaps in the near-infrared region to suppress penetration of thermal radiation. Experimental results show that the energy-saving glass decreases temperature increment in a mini-house. Moreover, the temperature after thermal equilibrium is lower than that inside a counterpart using ordinary glass.

关键词： energy-saving glass     photonic crystals     polystyrene spheres     self-assembly    

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标题 作者 时间 类型 操作

Progress of three-dimensional macroporous bioactive glass for bone regeneration

Lijun JI, Yunfeng SI, Ailing LI, Wenjun WANG, Dong QIU, Aiping ZHU

期刊论文

Development and clinical trial of a novel bioactive bone cement

LEONG John, LI Zhaoyang, LU William

期刊论文

Recent advances in small molecule fluorescent probes for simultaneous imaging of two bioactive molecules

Yongqing Zhou, Xin Wang, Wei Zhang, Bo Tang, Ping Li

期刊论文

An investigation into the properties of ternary and binary cement pastes containing glass powder

Marcelo Frota BAZHUNI, Mahsa KAMALI, Ali GHAHREMANINEZHAD

期刊论文

Precision glass molding: Toward an optimal fabrication of optical lenses

Liangchi ZHANG,Weidong LIU

期刊论文

Nonlinear analysis of pre-tensioned glass wall facade by stability function with initial imperfection

Siu-Lai CHAN, Yaopeng LIU, Andy LEE,

期刊论文

Bioactive hyaluronic acid fragments inhibit lipopolysaccharide-induced inflammatory responses via the

Na You, Sasa Chu, Binggang Cai, Youfang Gao, Mizhou Hui, Jin Zhu, Maorong Wang

期刊论文

Influence of damages on static behavior of single-layer cable net supported glass curtain wall: full-scale

Gang SHI, Yongjiu SHI, Yuanqing WANG, Yongzhi ZUO, Xiaohao SHI, Zaoyang GUO,

期刊论文

Recycled glass replacement as fine aggregate in self-compacting concrete

Yasser SHARIFI, Mahmoud HOUSHIAR, Behnam AGHEBATI

期刊论文

Review of small aspheric glass lens molding technologies

Shaohui YIN,Hongpeng JIA,Guanhua ZHANG,Fengjun CHEN,Kejun ZHU

期刊论文

Recent advancements in optical microstructure fabrication through glass molding process

Tianfeng ZHOU,Xiaohua LIU,Zhiqiang LIANG,Yang LIU,Jiaqing XIE,Xibin WANG

期刊论文

Assessment of glass fiber-reinforced polyester pipe powder in soil improvement

期刊论文

Mechanical properties of steel, glass, and hybrid fiber reinforced reactive powder concrete

Atheer H.M. ALGBURI, M. Neaz SHEIKH, Muhammad N.S. HADI

期刊论文

Fatigue shear performance of concrete beams reinforced with hybrid (glass-fiber-reinforced polymer+ steel

期刊论文

Realization of energy-saving glass using photonic crystals

Yen-Hsiang CHEN, Li-Hung LIAO, Yu-Bin CHEN

期刊论文